The final remaining relics Darkseid needed were being guarded by A.R.G.U.S. at their HQ, so Darkseid decided to use a Boom Tube to transport the building and all its contents to his base in the Amazon Rainforest. The Female Furies retrieved the relics and put them into place while Wonder Woman fought Darkseid. With the relics' power, Darkseid was able to open a portal to Themyscira. As it is impossible for one who has set foot on Themyscira to return after leaving, Diana was unable to follow Grail through the portal. Grail invaded and began transforming the Amazons into creatures resembling Darkseid's Parademons. As Jason had never actually set foot on Themyscira, he followed Grail and met his mother Hippolyta for the first time since his birth. While Jason and Hippolyta fought off the transformed Amazons, Wonder Woman was able to defeat Darkseid through her love for her deceased father, Zeus, and her half-siblings, calling their spirits out of Darkseid's body and destroying him from the inside. The Amazons captured Grail and imprisoned her in the prison beneath Themyscira, alongside Ares, while Darkseid re-emerged somewhere on Earth. Jason was gifted a magical spear from his mother and returned to Earth.
This new era of the comic book was influenced by the British television series The Avengers, with Wonder Woman in the role of Emma Peel. With Diana Prince running a boutique, fighting crime, and acting in concert with private detective allies Tim Trench and Jonny Double, the character resembled the Golden Age Black Canary. Soon after the launch of the "new" Wonder Woman, the editors severed all connections to her old life, most notably by killing Steve Trevor.
The British War Council quickly gathered to discuss the notebook. Their codebreakers were unable to decipher the two different languages that it was written in, but Diana quickly identified them as Ottoman and Sumerian. She read the book out loud, informing the council that Doctor Poison had created a new form of mustard gas based on hydrogen instead of sulfur, which gas masks would be useless against.
Having learnt of Wonder Woman's inability to return to Themyscira, Doctor Veronica Cale, a wealthy and powerful woman, set into motion a plan to use Wonder Woman to find Themyscira. Years earlier, Cale's daughter Izzy had her soul stolen by the gods Phobos and Deimos. They told Veronica that they would only return her daughter to her if she helped them find Wonder Woman, and got the location of Themyscira from her. Seeing no other option, Cale had formed a team called Godwatch, dedicated to locating Diana and Themyscira.
In 1954, Dr. Fredric Wertham alleged that there were lesbian subtexts to Wonder Woman and claimed comics contributed to juvenile delinquency in his book Seduction of the Innocent where despite a very obvious heterosexual relationship with Steve Trevor, Wertham asserted that Wonder Woman’s association with the Holliday Girls could be interpreted as a lesbian relationship. The Comics Code Authority was then introduced in reaction to Wertham 's claims against the entire industry.